Side effects
Most people tolerate CBD oil well, but there are some possible side effects.
According to a review in Cannabis and Cannabinoid Research, the most common side effects include:
In addition, using CBD oil with other medications may make those medications more or less effective.
The review also notes that scientists have yet to study some aspects of CBD, such as its long-term effects on hormones. Further long-term studies will be helpful in determining any side effects CBD has on the body over time.
People who are considering using CBD oil should discuss this with their doctors. Doctors will want to monitor the person for any changes and make adjustments accordingly.
People who are considering using CBD oil should discuss this with their doctors. Doctors will want to monitor the person for any changes and make adjustments accordingly.
Consult a doctor before using CBD, as it may interact with certain over-the-counter dietary supplements and medicines, as well as some prescription medications — especially those that warn against consuming grapefruit.
CBD might also interfere with an enzyme called cytochrome P450 complex. This disruption can affect the liver's ability to break down toxins, increasing the risk of liver toxicity.
CBD might also interfere with an enzyme called cytochrome P450 complex. This disruption can affect the liver's ability to break down toxins, increasing the risk of liver toxicity.
The patient information leaflet for Epidiolex cautions that there is a risk of liver damage, lethargy, and possibly depression and thoughts of suicide, but these are true of other treatments for epilepsy, too.
CBD and other cannabinoids may also put the user at risk for lung problems.
One study in Frontiers in Pharmacology suggested cannabinoids' anti-inflammatory effect may reduce inflammation too much.
A large reduction in inflammation could diminish the lungs' defense system, increasing the risk of infection.
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